Lat | linker for activation of T cells

GeneMGI:1342293

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal vitreous body morphology	2 supporting datasets	Lat^em1(IMPC)Ics	homozygote	Early adult	7.6x10^-9
increased circulating bilirubin level	1 supporting dataset	Lat^em1(IMPC)Ics	homozygote	Early adult	8.92x10^-7
abnormal startle reflex	1 supporting dataset	Lat^em1(IMPC)Ics	homozygote	Early adult	1.24x10^-15

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lat.

Associated images

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Histopathology

There is no histopathology data found for Lat.

IMPC related publications

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External links

No external links available for Lat.

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*Lat^em1(IMPC)Ics*	Deletion	‌	mouse
*Lat^{tm1(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Lat^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell

My Genes