Flii | flightless I actin binding protein

GeneMGI:1342286Synonyms: 3632430F08Rik, Fliih

Physiological systems

22 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Embryo Growth/size/body region Mortality/aging Renal/urinary system

18 No significant impact

2 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
29Embryo tissues

Phenotypes

abnormal embryo size1 supporting datasetFliitm1b(KOMP)MbphomozygoteE9.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsFliitm1b(KOMP)MbphomozygoteEarly adultN/A * 
embryonic growth retardation1 supporting datasetFliitm1b(KOMP)MbphomozygoteE9.5N/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetFliitm1b(KOMP)MbphomozygoteE12.5N/A * 
abnormal kidney morphology1 supporting datasetFliitm1b(KOMP)MbpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fliitm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Fliitm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Fliitm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse
Fliitm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

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