Aicda | activation-induced cytidine deaminase

GeneMGI:1342279Synonyms: Aid

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Immune system Hematopoietic system

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased germinal center B cell number4 supporting datasetsAicdatm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
decreased late germinal center B cell number2 supporting datasetsAicdatm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
decreased follicular B cell number1 supporting datasetAicdatm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
increased early germinal center B cell number3 supporting datasetsAicdatm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
increased mean corpuscular hemoglobin concentration1 supporting datasetAicdatm1b(EUCOMM)HmguhomozygoteEarly adult7.45x10-5 
increased leukocyte cell number1 supporting datasetAicdatm1b(EUCOMM)HmguhomozygoteEarly adult1.62x10-5 
increased mean corpuscular hemoglobin1 supporting datasetAicdatm1b(EUCOMM)HmguhomozygoteEarly adult9.94x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Aicdatm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Aicdatm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Aicdatm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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