Ehd1 | EH-domain containing 1

GeneMGI:1341878Synonyms: RME-1, Past1

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye

17 No significant impact

5 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

increased circulating HDL cholesterol level1 supporting datasetEhd1tm1a(EUCOMM)WtsiheterozygoteEarly adult9.2x10-5 
increased circulating cholesterol level1 supporting datasetEhd1tm1a(EUCOMM)WtsiheterozygoteEarly adult3.2x10-5 
abnormal eyelid aperture1 supporting datasetEhd1tm1a(EUCOMM)WtsihomozygoteEarly adult4.83x10-6 
increased circulating alanine transaminase level1 supporting datasetEhd1tm1a(EUCOMM)WtsiheterozygoteEarly adult1.99x10-5 
increased circulating LDL cholesterol level1 supporting datasetEhd1tm1a(EUCOMM)WtsiheterozygoteEarly adult6.13x10-5 
increased circulating chloride level1 supporting datasetEhd1tm1a(EUCOMM)WtsiheterozygoteEarly adult5.44x10-13 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ehd1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Ehd1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Ehd1tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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