Rb1cc1 | RB1-inducible coiled-coil 1

GeneMGI:1341850Synonyms: Fip200, Cc1, +3 more

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Embryo Growth/size/body region Vision/eye Mortality/aging Cardiovascular system

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal placenta vasculature	1 supporting dataset	Rb1cc1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
abnormal placenta morphology	1 supporting dataset	Rb1cc1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Rb1cc1^em1(IMPC)Mbp	heterozygote	E9.5	N/A ^*
abnormal heart morphology	1 supporting dataset	Rb1cc1^em1(IMPC)Mbp	heterozygote	E9.5	N/A ^*
abnormal vitelline vasculature morphology	1 supporting dataset	Rb1cc1^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Rb1cc1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
microphthalmia	1 supporting dataset	Rb1cc1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal visceral yolk sac morphology	1 supporting dataset	Rb1cc1^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Rb1cc1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rb1cc1.

Associated images

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Histopathology

There is no histopathology data found for Rb1cc1.

IMPC related publications

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External links

No external links available for Rb1cc1.

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*Rb1cc1^em1(IMPC)Mbp*	Inter-exon deletion	‌	mouse
*Rb1cc1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Rb1cc1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rb1cc1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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