Aqp6 | aquaporin 6

GeneMGI:1341204

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Renal/urinary system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating chloride level	1 supporting dataset	Aqp6^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.09x10^-5
abnormal kidney morphology	1 supporting dataset	Aqp6^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased total retina thickness	1 supporting dataset	Aqp6^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.37x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* Does not have a P-value assigned because it was manually marked as significant.

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lacZ Expression

No adult expression data available for Aqp6.

Associated images

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Histopathology

There is no histopathology data found for Aqp6.

IMPC related publications

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External links

No external links available for Aqp6.

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*Aqp6^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Aqp6^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Aqp6^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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