Sox30 | SRY (sex determining region Y)-box 30

GeneMGI:1341157

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:51Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina inner nuclear layer morphology	1 supporting dataset	Sox30^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.45x10^-5
increased fasting circulating glucose level	1 supporting dataset	Sox30^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.37x10^-5
persistence of hyaloid vascular system	1 supporting dataset	Sox30^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.29x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sox30.

Associated images

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Histopathology

There is no histopathology data found for Sox30.

IMPC related publications

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External links

No external links available for Sox30.

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*Sox30^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Sox30^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Sox30^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Sox30^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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