Sema3e | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Physiological systems
16 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Behavior/neurological Cardiovascular system
12 No significant impact
8 Not tested
Data collections
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| persistence of hyaloid vascular system | 1 supporting dataset | Sema3eem1(IMPC)H | homozygote | Early adult | 6.57x10-18 | ||
| irregularly shaped pupil | 1 supporting dataset | Sema3eem1(IMPC)H | homozygote | Early adult | 1.56x10-10 | ||
| abnormal placement of pupils | 1 supporting dataset | Sema3eem1(IMPC)H | homozygote | Early adult | 4x10-6 | ||
| decreased circulating phosphate level | 1 supporting dataset | Sema3eem1(IMPC)H | homozygote | Early adult | 1.34x10-5 | ||
| abnormal locomotor behavior | 1 supporting dataset | Sema3eem1(IMPC)H | homozygote | Early adult | 8.69x10-7 | ||
| abnormal retina blood vessel morphology | 1 supporting dataset | Sema3eem1(IMPC)H | homozygote | Early adult | 3.6x10-5 | ||
| impaired pupillary reflex | 1 supporting dataset | Sema3eem1(IMPC)H | homozygote | Early adult | 8.59x10-15 | ||
| abnormal retina morphology | 1 supporting dataset | Sema3eem1(IMPC)H | homozygote | Early adult | 1.15x10-16 |
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External links
No external links available for Sema3e.
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| Sema3eem1(IMPC)H | Exon Deletion | | mouse |
| Sema3eem2(IMPC)H | Exon Deletion | | mouse |
| Sema3etm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Sema3etm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |