Pak2 | p21 (RAC1) activated kinase 2
Physiological systems
16 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Mortality/aging
13 No significant impact
8 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Pak2em1(IMPC)H | homozygote | E12.5 | N/A * | ||
| increased circulating amylase level | 1 supporting dataset | Pak2em1(IMPC)H | heterozygote | Early adult | 2.39x10-6 | ||
| increased mean corpuscular hemoglobin | 1 supporting dataset | Pak2em1(IMPC)H | heterozygote | Early adult | 9.12x10-11 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Pak2em1(IMPC)H | homozygote | Early adult | N/A * | ||
| increased mean corpuscular volume | 1 supporting dataset | Pak2em1(IMPC)H | heterozygote | Early adult | 5.58x10-5 |
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External links
No external links available for Pak2.
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| Pak2em1(IMPC)H | Exon Deletion | | mouse |
| Pak2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Pak2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Pak2tm48006(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |