Pak1 | p21 (RAC1) activated kinase 1
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Nervous system Skeleton
14 No significant impact
6 Not tested
Data collections
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| increased circulating triglyceride level | 1 supporting dataset | Pak1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.26x10-8 | ||
| increased blood urea nitrogen level | 1 supporting dataset | Pak1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.45x10-8 | ||
| decreased bone mineral content | 1 supporting dataset | Pak1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.02x10-5 | ||
| increased total body fat amount | 1 supporting dataset | Pak1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.12x10-5 | ||
| decreased prepulse inhibition | 1 supporting dataset | Pak1tm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.99x10-5 |
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External links
No external links available for Pak1.
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| Pak1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Pak1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Pak1tm1c(EUCOMM)Hmgu | Wild type floxed exon (post-Flp) | | mouse |
| Pak1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |