Csf3r | colony stimulating factor 3 receptor
Physiological systems
21 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Reproductive system Endocrine/exocrine gland Mortality/aging
18 No significant impact
3 Not tested
Data collections
Gene metrics:3Significant phenotypes
6Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 2 supporting datasets | Csf3rtm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| small testis | 1 supporting dataset | Csf3rtm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| abnormal testis morphology | 1 supporting dataset | Csf3rtm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
| blood | heterozygote | n/a | 0% (0/2) | 0% (0/17) |
| bone marrow | heterozygote | Section images | 50% (1/2) | 0% (0/22) |
| brain | heterozygote | n/a | 0% (0/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | n/a | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | n/a | 0.22% (1/454) |
| cecum | heterozygote | n/a | 0% (0/1) | 7.75% (22/284) |
| cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
Human diseases caused by Csf3r mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Csf3r.
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| Csf3rtm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Csf3rtm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Csf3rtm214299(L1L2_Bact_P) | Reporter-tagged deletion allele (with selection cassette) | | targeting vector |