Cacna2d3 | calcium channel, voltage-dependent, alpha2/delta subunit 3

GeneMGI:1338890Synonyms: alpha 2 delta-3, alpha2delta3

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

17 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

decreased circulating glucose level1 supporting datasetCacna2d3tm1b(KOMP)WtsiheterozygoteEarly adult1.39x10-5 
increased circulating sodium level1 supporting datasetCacna2d3tm1b(KOMP)WtsiheterozygoteEarly adult1.17x10-5 
decreased circulating free fatty acids level1 supporting datasetCacna2d3tm1b(KOMP)WtsiheterozygoteEarly adult3.99x10-5 
decreased circulating triglyceride level1 supporting datasetCacna2d3tm1b(KOMP)WtsiheterozygoteEarly adult3.92x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cacna2d3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Cacna2d3tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Cacna2d3tm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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