Il18rap | interleukin 18 receptor accessory protein

GeneMGI:1338888Synonyms: AcPL accessory protein-like)

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Integument Vision/eye Hematopoietic system Behavior/neurological

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

male infertility1 supporting datasetIl18raptm1b(KOMP)WtsihomozygoteEarly adultN/A * 
abnormal hair growth1 supporting datasetIl18rapem1(IMPC)WtsihomozygoteEarly adult2.61x10-5 
decreased exploration in new environment1 supporting datasetIl18raptm1b(KOMP)WtsihomozygoteEarly adult4.5x10-10 
abnormal eye anterior chamber depth1 supporting datasetIl18raptm1b(KOMP)WtsihomozygoteEarly adult7.36x10-5 
decreased mean platelet volume1 supporting datasetIl18rapem1(IMPC)WtsihomozygoteEarly adult2.91x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Il18rapem1(IMPC)WtsiDeletionmouse
Il18raptm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Il18raptm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Il18raptm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Il18raptm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Il18raptm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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