Btrc | beta-transducin repeat containing protein

GeneMGI:1338871Synonyms: Slimb, Fbw1a, +3 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

1Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



increased mean corpuscular volume	1 supporting dataset	Btrc^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.36x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Btrc^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.17x10^-13
increased monocyte cell number	1 supporting dataset	Btrc^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.6x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Btrc.

Associated images

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Histopathology

There is no histopathology data found for Btrc.

IMPC related publications

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External links

No external links available for Btrc.

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*Btrc^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Btrc^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Btrc^{tm1c(KOMP)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse
*Btrc^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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