P2rx4 | purinergic receptor P2X, ligand-gated ion channel 4

GeneMGI:1338859Synonyms: D5Ertd444e, P2X4

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Skeleton

18 No significant impact

4 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

abnormal clavicle morphology1 supporting datasetP2rx4tm1b(EUCOMM)WtsihomozygoteEarly adult1.07x10-5 
decreased mean corpuscular volume1 supporting datasetP2rx4tm1b(EUCOMM)WtsihomozygoteEarly adult2.05x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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P2rx4tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
P2rx4tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
P2rx4tm1c(EUCOMM)WtsiWild type floxed exon (post-Flp)mouse
P2rx4tm1e(EUCOMM)WtsiTargeted, non-conditional allelemouse
P2rx4tm40299(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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