Rnd2 | Rho family GTPase 2

GeneMGI:1338755Synonyms: Arhn, Rohn

Physiological systems

20 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Cardiovascular system Renal/urinary system

10 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal liver morphology	2 supporting datasets	Rnd2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal urinary bladder morphology	1 supporting dataset	Rnd2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Rnd2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Rnd2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged spleen	2 supporting datasets	Rnd2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Rnd2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
prolonged RR interval	1 supporting dataset	Rnd2^em1(IMPC)Mbp	homozygote	Early adult	9.2x10^-5
increased body length	1 supporting dataset	Rnd2^em1(IMPC)Mbp	homozygote	Late adult	5.27x10^-10
anophthalmia	1 supporting dataset	Rnd2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal pancreas morphology	1 supporting dataset	Rnd2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rnd2.

Associated images

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Histopathology

There is no histopathology data found for Rnd2.

IMPC related publications

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External links

No external links available for Rnd2.

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*Rnd2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Rnd2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rnd2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Rnd2^{tm44173(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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