Itgb8 | integrin beta 8

GeneMGI:1338035Synonyms: 4832412O06Rik

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Integument Vision/eye Mortality/aging

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:50Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal retina outer nuclear layer morphology	2 supporting datasets	Itgb8^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	4.73x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Itgb8^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Itgb8^{tm1b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*
abnormal skin coloration	1 supporting dataset	Itgb8^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.55x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Itgb8.

Associated images

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Histopathology

There is no histopathology data found for Itgb8.

IMPC related publications

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External links

No external links available for Itgb8.

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*Itgb8^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Itgb8^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes