Rev3l | REV3 like, DNA directed polymerase zeta catalytic subunit
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological Mortality/aging
12 No significant impact
7 Not tested
Data collections
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues
| increased mean corpuscular hemoglobin concentration | 1 supporting dataset | Rev3ltm1b(EUCOMM)Hmgu | heterozygote | Early adult | 6.47x10-6 | ||
| decreased blood urea nitrogen level | 1 supporting dataset | Rev3ltm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.06x10-5 | ||
| abnormal retina morphology | 1 supporting dataset | Rev3ltm1b(EUCOMM)Hmgu | heterozygote | Early adult | 6.17x10-5 | ||
| hyperactivity | 2 supporting datasets | Rev3ltm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.32x10-6 | ||
| decreased circulating creatinine level | 1 supporting dataset | Rev3ltm1b(EUCOMM)Hmgu | heterozygote | Early adult | 6.36x10-5 | ||
| cataract | 1 supporting dataset | Rev3ltm1b(EUCOMM)Hmgu | heterozygote | Early adult | 7.29x10-9 | ||
| decreased mean corpuscular volume | 1 supporting dataset | Rev3ltm1b(EUCOMM)Hmgu | heterozygote | Early adult | 7.28x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Rev3ltm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * |
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External links
No external links available for Rev3l.
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| Rev3ltm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Rev3ltm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Rev3ltm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |