Serf1 | small EDRK-rich factor 1

GeneMGI:1337114Synonyms: 4F5, m4F5

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Skeleton Cardiovascular system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating cholesterol level	1 supporting dataset	Serf1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	5.6x10^-12
decreased bone mineral density	1 supporting dataset	Serf1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.2x10^-5
increased circulating HDL cholesterol level	1 supporting dataset	Serf1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.67x10^-11
increased heart weight	1 supporting dataset	Serf1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	4.88x10^-5
decreased CD8-positive, alpha-beta T cell number	1 supporting dataset	Serf1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.3x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Serf1.

Associated images

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Histopathology

There is no histopathology data found for Serf1.

IMPC related publications

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External links

No external links available for Serf1.

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*Serf1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Serf1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Serf1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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