Rnf7 | ring finger protein 7

GeneMGI:1337096Synonyms: Sag, Rbx2

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Rnf7^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating triglyceride level	1 supporting dataset	Rnf7^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.04x10^-5
abnormal gait	1 supporting dataset	Rnf7^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	3.34x10^-6
increased circulating chloride level	1 supporting dataset	Rnf7^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.25x10^-5
abnormal response to tactile stimuli	1 supporting dataset	Rnf7^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.25x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rnf7.

Associated images

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Histopathology

There is no histopathology data found for Rnf7.

IMPC related publications

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External links

No external links available for Rnf7.

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*Rnf7^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Rnf7^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Rnf7^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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