Eftud2 | elongation factor Tu GTP binding domain containing 2

GeneMGI:1336880Synonyms: Snrp116, 116kDa, +1 more

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Muscle Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:18Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased circulating cholesterol level	1 supporting dataset	Eftud2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	5.36x10^-10
decreased startle reflex	1 supporting dataset	Eftud2^{tm1b(KOMP)Wtsi}	heterozygote	Late adult	2.13x10^-7
decreased exploration in new environment	1 supporting dataset	Eftud2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	4.31x10^-5
increased circulating total protein level	1 supporting dataset	Eftud2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	7.08x10^-8
increased heart left ventricle size	1 supporting dataset	Eftud2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.47x10^-11
increased circulating calcium level	1 supporting dataset	Eftud2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2.87x10^-12
thick ventricular wall	1 supporting dataset	Eftud2^{tm1b(KOMP)Wtsi}	heterozygote	Late adult	8.03x10^-5
abnormal heart left ventricle morphology	1 supporting dataset	Eftud2^{tm1b(KOMP)Wtsi}	heterozygote	Late adult	1.73x10^-5
decreased lymphocyte cell number	1 supporting dataset	Eftud2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.94x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Eftud2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Eftud2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Eftud2.

IMPC related publications

Loading...

External links

No external links available for Eftud2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Eftud2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Eftud2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes