Hs3st3a1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1

GeneMGI:1333861Synonyms: 3Ost3a

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Hematopoietic system Cardiovascular system

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased heart weight	2 supporting datasets	Hs3st3a1^{tm1(KOMP)Vlcg}	homozygote	Early adult	1.42x10^-5
increased circulating aspartate transaminase level	1 supporting dataset	Hs3st3a1^{tm1(KOMP)Vlcg}	homozygote	Early adult	1.92x10^-46
thrombocytopenia	1 supporting dataset	Hs3st3a1^{tm1(KOMP)Vlcg}	homozygote	Early adult	5.79x10^-5
increased circulating total protein level	1 supporting dataset	Hs3st3a1^{tm1(KOMP)Vlcg}	homozygote	Early adult	6.54x10^-5
decreased total body fat amount	1 supporting dataset	Hs3st3a1^{tm1(KOMP)Vlcg}	homozygote	Early adult	7x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Hs3st3a1^{tm1(KOMP)Vlcg}	homozygote	Early adult	2.97x10^-129

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hs3st3a1.

Associated images

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Histopathology

There is no histopathology data found for Hs3st3a1.

IMPC related publications

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External links

No external links available for Hs3st3a1.

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*Hs3st3a1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Hs3st3a1^{tm300133(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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