Mrpl22 | mitochondrial ribosomal protein L22

GeneMGI:1333794Synonyms: Rpml25, E030011D16Rik, +2 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

impaired pupillary reflex1 supporting datasetMrpl22tm1b(KOMP)MbpheterozygoteEarly adult4.04x10-6 
increased fasting circulating glucose level1 supporting datasetMrpl22tm1b(KOMP)MbpheterozygoteEarly adult6.04x10-5 
preweaning lethality, complete penetrance1 supporting datasetMrpl22tm1b(KOMP)MbphomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetMrpl22tm1b(KOMP)MbphomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Mrpl22tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Mrpl22tm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse
Mrpl22tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Mrpl22tm2a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Mrpl22tm2e(KOMP)MbpTargeted, non-conditional alleleES Cell
Mrpl22tm41846(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter