Bcl7c | B cell CLL/lymphoma 7C
Physiological systems
17 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Homeostasis/metabolism
16 No significant impact
7 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating calcium level | 1 supporting dataset | Bcl7cem1(IMPC)J | homozygote | Early adult | 6.18x10-6 | ||
| increased circulating creatinine level | 1 supporting dataset | Bcl7cem1(IMPC)J | homozygote | Early adult | 7.57x10-5 |
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Human diseases caused by Bcl7c mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Bcl7c.
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| Bcl7cem1(IMPC)J | Exon Deletion | | mouse |
| Bcl7ctm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Bcl7ctm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |