Lgmn | legumain

GeneMGI:1330838Synonyms: preprolegumain, Prsc1, +1 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Growth/size/body region Limbs/digits/tail Nervous system Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



short tibia	1 supporting dataset	Lgmn^{tm1b(NCOM)Mfgc}	homozygote	Early adult	3.2x10^-10
decreased body length	1 supporting dataset	Lgmn^{tm1b(NCOM)Mfgc}	homozygote	Early adult	6.07x10^-6
decreased prepulse inhibition	1 supporting dataset	Lgmn^{tm1b(NCOM)Mfgc}	homozygote	Early adult	4.9x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lgmn.

Associated images

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Histopathology

There is no histopathology data found for Lgmn.

IMPC related publications

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External links

No external links available for Lgmn.

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*Lgmn^{tm1a(NCOM)Mfgc}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Lgmn^{tm1b(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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