Atp9a | ATPase, class II, type 9A
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Vision/eye Behavior/neurological Cardiovascular system
17 No significant impact
4 Not tested
Data collections
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| hyperactivity | 4 supporting datasets | Atp9atm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.74x10-9 | ||
| increased exploration in new environment | 1 supporting dataset | Atp9atm1b(EUCOMM)Hmgu | homozygote | Early adult | 7.32x10-8 | ||
| abnormal retina blood vessel morphology | 1 supporting dataset | Atp9atm1b(EUCOMM)Hmgu | homozygote | Early adult | 6.75x10-5 |
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Human diseases caused by Atp9a mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Atp9a.
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| Atp9atm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Atp9atm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Atp9atm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |