Qsox1 | quiescin Q6 sulfhydryl oxidase 1

GeneMGI:1330818Synonyms: QSOX, 1300003H02Rik, +2 more

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Integument Growth/size/body region Nervous system Behavior/neurological Cardiovascular system

10 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/hair pigmentation2 supporting datasetsQsox1em1(IMPC)KmpchomozygoteLate adult3.48x10-6 
increased circulating lactate dehydrogenase level1 supporting datasetQsox1em1(IMPC)KmpchomozygoteLate adult1.14x10-5 
increased grip strength1 supporting datasetQsox1em1(IMPC)KmpchomozygoteLate adult7.55x10-6 
abnormal skin coloration1 supporting datasetQsox1em1(IMPC)KmpchomozygoteLate adult7.33x10-6 
increased heart weight1 supporting datasetQsox1em1(IMPC)KmpchomozygoteLate adult6.2x10-5 
decreased fasting circulating glucose level1 supporting datasetQsox1em1(IMPC)KmpchomozygoteLate adult1.32x10-5 
decreased prepulse inhibition1 supporting datasetQsox1em1(IMPC)KmpchomozygoteLate adult1.44x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Qsox1em1(IMPC)KmpcDeletionmouse
Qsox1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Qsox1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Qsox1tm43918(L1L2_st1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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