Krtap8-1 | keratin associated protein 8-1

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased exploration in new environment	1 supporting dataset	Krtap8-1^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.42x10^-5
decreased T-helper cell number	1 supporting dataset	Krtap8-1^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.24x10^-5
decreased body weight	1 supporting dataset	Krtap8-1^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.64x10^-5
abnormal uterus morphology	1 supporting dataset	Krtap8-1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
lordosis	1 supporting dataset	Krtap8-1^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.24x10^-7
hydrometra	1 supporting dataset	Krtap8-1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal retina morphology	1 supporting dataset	Krtap8-1^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.2x10^-5
abnormal heart morphology	1 supporting dataset	Krtap8-1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Krtap8-1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased CD4-positive, alpha-beta T cell number	1 supporting dataset	Krtap8-1^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.52x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Krtap8-1.

Associated images

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Histopathology

There is no histopathology data found for Krtap8-1.

IMPC related publications

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External links

No external links available for Krtap8-1.

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*Krtap8-1^{em1(IMPC)Ccpcz}*	Whole-gene deletion	‌	mouse

My Genes