Clcnka | chloride channel, voltage-sensitive Ka

GeneMGI:1329026Synonyms: CLC-K1, Clcnk1

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

7Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



increased circulating alkaline phosphatase level	1 supporting dataset	Clcnka^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.93x10^-6
increased circulating chloride level	1 supporting dataset	Clcnka^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	3.07x10^-6
decreased total body fat amount	1 supporting dataset	Clcnka^{tm1b(EUCOMM)Hmgu}	homozygote	Late adult	1.4x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Clcnka.

Associated images

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Histopathology

There is no histopathology data found for Clcnka.

IMPC related publications

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External links

No external links available for Clcnka.

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*Clcnka^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Clcnka^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Clcnka^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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