Ccnt1 | cyclin T1

GeneMGI:1328363Synonyms: CycT1, 2810478G24Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Vision/eye Hematopoietic system Behavior/neurological

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex1 supporting datasetCcnt1em1(IMPC)JhomozygoteEarly adult9.37x10-8 
decreased erythrocyte cell number1 supporting datasetCcnt1em1(IMPC)JhomozygoteEarly adult5.72x10-6 
increased mean corpuscular hemoglobin1 supporting datasetCcnt1em1(IMPC)JhomozygoteEarly adult1.47x10-9 
increased leukocyte cell number1 supporting datasetCcnt1em1(IMPC)JheterozygoteEarly adult4.64x10-13 
persistence of hyaloid vascular system1 supporting datasetCcnt1em1(IMPC)JhomozygoteEarly adult2.78x10-7 
increased circulating alkaline phosphatase level1 supporting datasetCcnt1em1(IMPC)JhomozygoteEarly adult1.29x10-17 
decreased circulating total protein level1 supporting datasetCcnt1em1(IMPC)JhomozygoteEarly adult1.98x10-6 
decreased exploration in new environment1 supporting datasetCcnt1em1(IMPC)JhomozygoteEarly adult5.56x10-5 
increased mean corpuscular volume1 supporting datasetCcnt1em1(IMPC)JhomozygoteEarly adult3.01x10-7 
increased leukocyte cell number1 supporting datasetCcnt1em1(IMPC)JhomozygoteEarly adult1.73x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ccnt1em1(IMPC)JExon Deletionmouse
Ccnt1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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