Mpp3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)

GeneMGI:1328354Synonyms: Dlgh3

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Muscle Cardiovascular system

15 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

decreased circulating glucose level1 supporting datasetMpp3tm1b(EUCOMM)WtsihomozygoteEarly adult8.61x10-5 
abnormal heart left ventricle morphology4 supporting datasetsMpp3tm1b(EUCOMM)WtsihomozygoteEarly adult4.85x10-12 
increased cardiac muscle contractility2 supporting datasetsMpp3tm1b(EUCOMM)WtsihomozygoteEarly adult1.23x10-11 
thick ventricular wall2 supporting datasetsMpp3tm1b(EUCOMM)WtsihomozygoteEarly adult4.98x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mpp3tm1(EGFP_CreERT2)WtsiReporter-tagged deletion allele (with selection cassette)ES Cell
Mpp3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Mpp3tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Mpp3tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Mpp3tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Mpp3tm88(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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