Syngr1 | synaptogyrin 1
Physiological systems
22 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Muscle Hematopoietic system
16 No significant impact
2 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged lymph nodes | 2 supporting datasets | Syngr1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal lymph node morphology | 2 supporting datasets | Syngr1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal uterus morphology | 1 supporting dataset | Syngr1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 2 supporting datasets | Syngr1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal skeletal muscle morphology | 1 supporting dataset | Syngr1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| enlarged uterus | 1 supporting dataset | Syngr1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| enlarged spleen | 2 supporting datasets | Syngr1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| enlarged thymus | 1 supporting dataset | Syngr1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal thymus morphology | 1 supporting dataset | Syngr1em1(IMPC)Ccpcz | homozygote | Early adult | N/A * |
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Human diseases caused by Syngr1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Syngr1.
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| Syngr1em1(IMPC)Ccpcz | Exon Deletion | | mouse |
| Syngr1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Syngr1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Syngr1tm42664(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |