Orc2 | origin recognition complex, subunit 2

GeneMGI:1328306Synonyms: Orc2l

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

limb grasping1 supporting datasetOrc2em1(IMPC)JheterozygoteEarly adult2.57x10-5 
preweaning lethality, complete penetrance1 supporting datasetOrc2em1(IMPC)JhomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetOrc2em1(IMPC)JhomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Orc2em1(IMPC)JExon Deletionmouse
Orc2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Orc2tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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