Cox7a2 | cytochrome c oxidase subunit 7A2

GeneMGI:1316715Synonyms: COX7AL, Cox7a3

Physiological systems

22 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Behavior/neurological

18 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased total body fat amount2 supporting datasetsCox7a2tm1b(EUCOMM)HmguheterozygoteLate adult8.34x10-19 
increased lean body mass2 supporting datasetsCox7a2tm1b(EUCOMM)HmguheterozygoteLate adult6.43x10-22 
increased food intake1 supporting datasetCox7a2tm1b(EUCOMM)HmguheterozygoteLate adult3.02x10-7 
increased respiratory quotient1 supporting datasetCox7a2tm1b(EUCOMM)HmguheterozygoteLate adult5.89x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cox7a2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Cox7a2tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Cox7a2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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