Emg1 | EMG1 N1-specific pseudouridine methyltransferase
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Mortality/aging
17 No significant impact
4 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues
| decreased total retina thickness | 2 supporting datasets | Emg1tm1.1(KOMP)Wtsi | heterozygote | Early adult | 4.59x10-7 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Emg1tm1.1(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Emg1tm1.1(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| abnormal retina inner nuclear layer morphology | 2 supporting datasets | Emg1tm1.1(KOMP)Wtsi | heterozygote | Early adult | 1.26x10-6 | ||
| decreased circulating aspartate transaminase level | 1 supporting dataset | Emg1tm1.1(KOMP)Wtsi | heterozygote | Early adult | 1.46x10-5 |
| | | | | | | | | | |
External links
No external links available for Emg1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Emg1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Emg1tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector es cell mouse |
| Emg1tm1.1(KOMP)Wtsi | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Emg1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |