Eif2b3 | eukaryotic translation initiation factor 2B, subunit 3
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Hematopoietic system Mortality/aging
17 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
6Associated diseases
Expression examined in:46Adult tissues
21Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Eif2b3tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased mean corpuscular hemoglobin | 1 supporting dataset | Eif2b3tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 8.23x10-5 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Eif2b3tm1b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
| decreased hemoglobin content | 1 supporting dataset | Eif2b3tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.78x10-5 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Eif2b3tm1b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * |
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External links
No external links available for Eif2b3.
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| Eif2b3tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Eif2b3tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Eif2b3tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |