Gstm6 | glutathione S-transferase, mu 6

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Nervous system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating glucose level1 supporting datasetGstm6tm1b(EUCOMM)HmguhomozygoteEarly adult1.4x10-6 
decreased prepulse inhibition2 supporting datasetsGstm6tm1b(EUCOMM)HmguhomozygoteEarly adult2.58x10-5 
increased circulating phosphate level1 supporting datasetGstm6tm1b(EUCOMM)HmguhomozygoteEarly adult5.36x10-5 
increased total body fat amount1 supporting datasetGstm6tm1b(EUCOMM)HmguhomozygoteEarly adult1.16x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Gstm6 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Gstm6tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Gstm6tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Gstm6tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Gstm6tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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