Gstm6 | glutathione S-transferase, mu 6
GeneMGI:1309467
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Nervous system
16 No significant impact
5 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased circulating glucose level | 1 supporting dataset | Gstm6tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.4x10-6 | ||
decreased prepulse inhibition | 2 supporting datasets | Gstm6tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.58x10-5 | ||
increased circulating phosphate level | 1 supporting dataset | Gstm6tm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.36x10-5 | ||
increased total body fat amount | 1 supporting dataset | Gstm6tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.16x10-5 |
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Human diseases caused by Gstm6 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Gstm6.
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Gstm6tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
Gstm6tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Gstm6tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Gstm6tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |