Ccdc39 | coiled-coil domain containing 39

GeneMGI:1289263Synonyms: b2b1304Clo, b2b1735Clo, +4 more

Physiological systems

21 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

20 No significant impact

3 Not tested

Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance2 supporting datasetsCcdc39tm2b(KOMP)WtsihomozygoteEarly adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetCcdc39tm2b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a0% (0/2)0.7% (4/570)
aortaheterozygoten/a0% (0/2)0.19% (1/533)
bloodheterozygoten/a0% (0/2)0% (0/17)
bone marrowheterozygoten/a0% (0/2)0% (0/22)
brainheterozygoten/a100% (2/2)0.86% (5/579)
brainstemheterozygoten/an/a0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoten/an/a0.22% (1/454)
cecumheterozygoten/a0% (0/2)7.75% (22/284)
cerebellumheterozygoten/a0% (0/2)0.56% (3/532)
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Histopathology

IMPC related publications

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Ccdc39tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
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Ccdc39tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
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