Tmem41b | transmembrane protein 41B

GeneMGI:1289225Synonyms: 1500015G02Rik, 1500031M19Rik, +2 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

64Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Tmem41b^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Tmem41b^{tm1b(KOMP)Wtsi}	homozygote	E9.5	N/A ^*
increased circulating creatine kinase level	1 supporting dataset	Tmem41b^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	9.19x10^-5
embryonic lethality prior to tooth bud stage	1 supporting dataset	Tmem41b^{tm1b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem41b.

Associated images

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Histopathology

There is no histopathology data found for Tmem41b.

IMPC related publications

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External links

No external links available for Tmem41b.

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*Tmem41b^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tmem41b^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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