Fbxo36 | F-box protein 36

GeneMGI:1289192Synonyms: 2410002G19Rik, 1110020F21Rik, +2 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Hematopoietic system Behavior/neurological Cardiovascular system

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased mean platelet volume	1 supporting dataset	Fbxo36^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.75x10^-11
decreased mean corpuscular volume	1 supporting dataset	Fbxo36^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.54x10^-29
decreased monocyte cell number	2 supporting datasets	Fbxo36^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.4x10^-7
increased neutrophil cell number	1 supporting dataset	Fbxo36^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.94x10^-5
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Fbxo36^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.56x10^-14
thrombocytopenia	1 supporting dataset	Fbxo36^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.54x10^-8
abnormal heart left ventricle morphology	1 supporting dataset	Fbxo36^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.19x10^-6
decreased hematocrit	1 supporting dataset	Fbxo36^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.28x10^-9
decreased grip strength	2 supporting datasets	Fbxo36^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.39x10^-5
increased basophil cell number	1 supporting dataset	Fbxo36^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.73x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fbxo36.

Associated images

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Histopathology

There is no histopathology data found for Fbxo36.

IMPC related publications

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External links

No external links available for Fbxo36.

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*Fbxo36^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Fbxo36^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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