Adgra1 | adhesion G protein-coupled receptor A1

GeneMGI:1277167Synonyms: 2900059M17Rik, D7Ertd680e, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Skeleton Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Allele:

Phy. System:



improved glucose tolerance	1 supporting dataset	Adgra1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.79x10^-6
preweaning lethality, incomplete penetrance	1 supporting dataset	Adgra1^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased bone mineral content	1 supporting dataset	Adgra1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.45x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression



adrenal gland	heterozygote	Section images	100% (2/2)	0.7% (4/570)
aorta	heterozygote	n/a	0% (0/2)	0.19% (1/533)
brain	heterozygote	Section images	100% (2/2)	0.86% (5/579)
brainstem	heterozygote	Section images	100% (2/2)	0.41% (2/490)
brown adipose tissue	heterozygote	n/a	0% (0/2)	0% (0/588)
cartilage tissue	heterozygote	n/a	0% (0/2)	0.22% (1/454)
cerebellum	heterozygote	Section images	100% (2/2)	0.56% (3/532)
cerebral cortex	heterozygote	Section images	100% (2/2)	0.41% (2/491)
epididymis	heterozygote	n/a	0% (0/1)	87.5% (21/24)
esophagus	heterozygote	n/a	0% (0/2)	1.67% (7/419)

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Associated images

18 images

Adult LacZ

LacZ Images Section

Download files

Auditory Brain Stem Response

Click-evoked + 6 to 30kHz tone waveforms (pdf format)

Download files

Electroretinography 2

Rod and cone PDF

12 images

Embryo LacZ

LacZ images wholemount

12 images

Eye Morphology

Images Ophthalmoscopy

1 images

Eye Morphology

Images Slit Lamp

6 images

Sleep Wake

Wake state (bmp file)

20 images

X-ray

XRay Images Forepaw

20 images

X-ray

XRay Images Skull Dorso Ventral Orientation

20 images

X-ray

XRay Images Skull Lateral Orientation

20 images

X-ray

XRay Images Whole Body Dorso Ventral

20 images

X-ray

XRay Images Whole Body Lateral Orientation

Histopathology

There is no histopathology data found for Adgra1.

IMPC related publications

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External links

No external links available for Adgra1.

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*Adgra1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Adgra1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Adgra1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Adgra1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

My Genes

Adgra1 | adhesion G protein-coupled receptor A1

Physiological systems

3 Significantly impacted by the knock-out

15 No significant impact

6 Not tested

Data collections

Phenotypes

lacZ Expression

Associated images

Adult LacZ

Auditory Brain Stem Response

Electroretinography 2

Embryo LacZ

Eye Morphology

Eye Morphology

Sleep Wake

X-ray

X-ray

X-ray

X-ray

X-ray

Histopathology

IMPC related publications

External links

Order Mouse and ES Cells

The IMPC Newsletter

Access Data Release 22.1 Data