Vax1 | ventral anterior homeobox 1

GeneMGI:1277163

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging Cardiovascular system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:50Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Vax1^{tm1b(KOMP)Mbp}	homozygote	Early adult	N/A ^*
abnormal sinus arrhythmia	1 supporting dataset	Vax1^{tm1b(KOMP)Mbp}	heterozygote	Early adult	6.49x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Vax1^{tm1b(KOMP)Mbp}	heterozygote	Early adult	2.23x10^-5
decreased circulating glucose level	1 supporting dataset	Vax1^{tm1b(KOMP)Mbp}	heterozygote	Early adult	7.39x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Vax1.

Associated images

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Histopathology

There is no histopathology data found for Vax1.

IMPC related publications

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External links

No external links available for Vax1.

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*Vax1^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Vax1^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Vax1^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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