Cacybp | calcyclin binding protein

GeneMGI:1270839

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Mortality/aging

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Cacybp^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased neutrophil cell number	1 supporting dataset	Cacybp^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.58x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Cacybp^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.97x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cacybp.

Associated images

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Histopathology

There is no histopathology data found for Cacybp.

IMPC related publications

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External links

No external links available for Cacybp.

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*Cacybp^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Cacybp^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cacybp^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cacybp^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Cacybp^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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