Dnaja1 | DnaJ heat shock protein family (Hsp40) member A1

GeneMGI:1270129Synonyms: Nedd7, Hsj2

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

46Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating sodium level	1 supporting dataset	Dnaja1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.18x10^-11
hyperactivity	2 supporting datasets	Dnaja1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	5.81x10^-5
increased grip strength	2 supporting datasets	Dnaja1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2x10^-5
decreased grip strength	1 supporting dataset	Dnaja1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.13x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Dnaja1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dnaja1.

Associated images

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Histopathology

There is no histopathology data found for Dnaja1.

IMPC related publications

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External links

No external links available for Dnaja1.

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*Dnaja1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Dnaja1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Dnaja1^{tm358548(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes