Fbxo41 | F-box protein 41

GeneMGI:1261912Synonyms: D6Ertd538e

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hearing/vestibular/ear Vision/eye Behavior/neurological Cardiovascular system Renal/urinary system

14 No significant impact

3 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

hyperactivity4 supporting datasetsFbxo41tm1.1(KOMP)VlcghomozygoteEarly adult5.58x10-6 
increased heart weight1 supporting datasetFbxo41tm1.1(KOMP)VlcghomozygoteEarly adult5.11x10-5 
decreased grip strength1 supporting datasetFbxo41tm1.1(KOMP)VlcghomozygoteEarly adult2.98x10-5 
eye hemorrhage1 supporting datasetFbxo41tm1.1(KOMP)VlcghomozygoteEarly adult6.16x10-5 
abnormal auditory brainstem response1 supporting datasetFbxo41tm1.1(KOMP)VlcghomozygoteEarly adult1.79x10-5 
decreased circulating cholesterol level1 supporting datasetFbxo41tm1.1(KOMP)VlcghomozygoteEarly adult9.01x10-5 
increased kidney weight1 supporting datasetFbxo41tm1.1(KOMP)VlcghomozygoteEarly adult1.07x10-6 
increased startle reflex1 supporting datasetFbxo41tm1.1(KOMP)VlcghomozygoteEarly adult6.26x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Fbxo41tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Fbxo41tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter