Fbxo28 | F-box protein 28

GeneMGI:1261890Synonyms: Fbx28, D1Ertd578e, +2 more

Physiological systems

15 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Hematopoietic system Behavior/neurological

12 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased grip strength2 supporting datasetsFbxo28em1(IMPC)MhzhheterozygoteEarly adult5.46x10-6 
increased basophil cell number2 supporting datasetsFbxo28em1(IMPC)MhzhheterozygoteEarly adult3.78x10-16 
decreased thigmotaxis2 supporting datasetsFbxo28em1(IMPC)MhzhheterozygoteEarly adult6.84x10-5 
increased eosinophil cell number2 supporting datasetsFbxo28em1(IMPC)MhzhheterozygoteEarly adult4.34x10-17 
abnormal behavior1 supporting datasetFbxo28em1(IMPC)MhzhheterozygoteEarly adult6.85x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fbxo28em1(IMPC)MhzhIndelmouse
Fbxo28tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Fbxo28tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Fbxo28tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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