Fbxo28 | F-box protein 28
Physiological systems
15 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Immune system Hematopoietic system Behavior/neurological
12 No significant impact
9 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased grip strength | 2 supporting datasets | Fbxo28em1(IMPC)Mhzh | heterozygote | Early adult | 5.46x10-6 | ||
increased basophil cell number | 2 supporting datasets | Fbxo28em1(IMPC)Mhzh | heterozygote | Early adult | 3.78x10-16 | ||
decreased thigmotaxis | 2 supporting datasets | Fbxo28em1(IMPC)Mhzh | heterozygote | Early adult | 6.84x10-5 | ||
increased eosinophil cell number | 2 supporting datasets | Fbxo28em1(IMPC)Mhzh | heterozygote | Early adult | 4.34x10-17 | ||
abnormal behavior | 1 supporting dataset | Fbxo28em1(IMPC)Mhzh | heterozygote | Early adult | 6.85x10-5 |
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Human diseases caused by Fbxo28 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Fbxo28.
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Fbxo28em1(IMPC)Mhzh | Indel | | mouse |
Fbxo28tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
Fbxo28tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Fbxo28tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |