Ankle2 | ankyrin repeat and LEM domain containing 2

GeneMGI:1261856Synonyms: 1110001J12Rik, D5Ertd585e

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Vision/eye Behavior/neurological Mortality/aging Cardiovascular system

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	3 supporting datasets	Ankle2^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
increased exploration in new environment	1 supporting dataset	Ankle2^em1(IMPC)Bay	heterozygote	Early adult	1.66x10^-5
thin ventricular wall	1 supporting dataset	Ankle2^em1(IMPC)Bay	heterozygote	Early adult	7.3x10^-7
abnormal retina vasculature morphology	1 supporting dataset	Ankle2^em1(IMPC)Bay	heterozygote	Early adult	3.57x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Ankle2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Ankle2.

IMPC related publications

Loading...

External links

No external links available for Ankle2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Ankle2^em1(IMPC)Bay*	Exon Deletion	‌	mouse

My Genes