Vps37a | vacuolar protein sorting 37A

GeneMGI:1261835Synonyms: 2210018P21Rik, 4930592A21Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Integument Embryo Growth/size/body region Behavior/neurological Mortality/aging

15 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased freezing behavior1 supporting datasetVps37aem1(IMPC)TcpheterozygoteEarly adult1.28x10-6 
preweaning lethality, complete penetrance3 supporting datasetsVps37aem1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal coat/ hair morphology1 supporting datasetVps37aem1(IMPC)TcpheterozygoteEarly adult1.28x10-7 
abnormal embryo size1 supporting datasetVps37aem1(IMPC)TcphomozygoteE15.5N/A * 
decreased body length1 supporting datasetVps37aem1(IMPC)TcpheterozygoteEarly adult9.33x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Vps37aem1(IMPC)TcpExon Deletionmouse
Vps37atm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Vps37atm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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