Hap1 | huntingtin-associated protein 1

GeneMGI:1261831Synonyms: HAP-1

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Hap1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased blood urea nitrogen level	1 supporting dataset	Hap1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.15x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hap1.

Associated images

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Histopathology

There is no histopathology data found for Hap1.

IMPC related publications

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External links

No external links available for Hap1.

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*Hap1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Hap1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Hap1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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