Cand1 | cullin associated and neddylation disassociated 1

GeneMGI:1261820Synonyms: D10Ertd516e, 6330512O03Rik, +1 more

Physiological systems

22 / 24 physiological systems tested

14 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system Cardiovascular system Craniofacial Renal/urinary system Homeostasis/metabolism Embryo Vision/eye Liver/biliary system Mortality/aging

8 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:24Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal spleen morphology	1 supporting dataset	Cand1^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
small testis	1 supporting dataset	Cand1^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
enlarged gallbladder	1 supporting dataset	Cand1^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
microphthalmia	1 supporting dataset	Cand1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
enlarged spleen	2 supporting datasets	Cand1^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Cand1^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
edema	1 supporting dataset	Cand1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Cand1^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal blood vessel morphology	1 supporting dataset	Cand1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal placenta morphology	1 supporting dataset	Cand1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cand1.

Associated images

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Histopathology

There is no histopathology data found for Cand1.

IMPC related publications

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External links

No external links available for Cand1.

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*Cand1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Cand1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Cand1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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